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Abstract:
The balanced steady-state free precession (bSSFP) profile is known to carry information about the tissue-dependent frequency content in a voxel. There has been strong evidence that the observed asymmetries in the bSSFP profile of white matter depend on the tract orientation with the largest asymmetries occurring in tracts perpendicular to B0. Recently, it was demonstrated that the bSSFP sequence can be used for chemical exchange detection based on profile asymmetries arising in isotropic probes of two exchanging pools. In this work, we explore the question whether exchanging species might contribute to the bSSFP profile asymmetry observed in white matter.
