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  MRI of whole brain formalin-fixed samples at 9.4T: influence of the fixation agent and its dielectric properties on image quality

Hagberg, G., Shiozawa-Bayer, T., Mirkes, C., Engelmann, J., Bause, J., Hirt, B., et al. (2018). MRI of whole brain formalin-fixed samples at 9.4T: influence of the fixation agent and its dielectric properties on image quality. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0001-7DC8-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0001-9343-D
Genre: Poster

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 Creators:
Hagberg, GE1, 2, Author              
Shiozawa-Bayer, T, Author
Mirkes, C1, 2, Author              
Engelmann, J, Author              
Bause, J1, 2, Author              
Hirt, B, Author
Scheffler, K1, 2, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: MRI of post mortem samples in formalin is an essential tool for validation purposes and comparison with clinical histology, since fixation preserve several microstructural tissue features. We found that the dielectric properties of the fixative influences image quality attained in whole brain post mortem samples at 9.4T. The standard fixative prevented high quality MRI across the entire sample. By using a high conductivity fixative with less field focussing, a more homogeneous excitation was achieved without any drop outs and T1 mapping could be performed using rapid inversion recovery techniques.

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 Dates: 2018-06
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: HagbergSMEBHS2018
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3310 Start / End Page: - Identifier: -