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  Relaxation-compensated multi-pool CEST signal at 7T MRI of WHO IV gliomas is dependent on the anatomic localization

Dreher, C., Oberhollenzer, J., Windschuh, J., Meissner, J.-E., Sahm, F., Bendszus, M., et al. (2018). Relaxation-compensated multi-pool CEST signal at 7T MRI of WHO IV gliomas is dependent on the anatomic localization. Poster presented at Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0001-7DCC-E Version Permalink: https://hdl.handle.net/21.11116/0000-0001-934B-5
Genre: Poster

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https://www.ismrm.org/18/Electronic_Posters.pdf (Abstract)
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 Creators:
Dreher, C, Author
Oberhollenzer, J, Author
Windschuh, J, Author
Meissner, J-E, Author
Sahm, F, Author
Bendszus, M, Author
Unterberg, A, Author
Wick, W, Author
Bachert, P, Author
Ladd, ME, Author
Schlemmer, H-P, Author
Zaiss, M1, 2, Author           
Radbruch, A, Author
Paech, D, Author
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: As patients with WHO IV° gliomas are still having a dismal prognosis, further tumor characterization is needed. With prognosis and histopathological parameters being dependent on tumor localization, and Chemical-Exchange-Saturation-Transfer(CEST) MRI at 7T being one of the latest advances in tumor imaging, we have prospectively evaluated CEST signals in 21 patients. Amide CEST and ADC parameters are significantly different with regard to brain hemispheres and correlating. CEST NOE(Nuclear Overhauser-Effect) is not different with regard to brain hemispheres, but in case of contact to the subventricular zone, which is accompanied by worse prognosis. NOE is possibly showing complementary information to Amide CEST.

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 Dates: 2018-06
 Publication Status: Issued
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 Identifiers: BibTex Citekey: DreherOWMSBUWBLSZRP2018
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3591 Start / End Page: - Identifier: -