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  Correlation between APT-CEST and 18F-Choline PET in glioma at 3T

Rega, M., Torrealdea, F., Hearle, J., Zaiss, M., Carvalho, A., Asaf, A., et al. (2018). Correlation between APT-CEST and 18F-Choline PET in glioma at 3T. In Joint Annual Meeting ISMRM-ESMRMB 2018.

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 Creators:
Rega, M, Author
Torrealdea, F, Author
Hearle, J, Author
Zaiss, M1, 2, Author           
Carvalho, A, Author
Asaf, A, Author
Punwani, S, Author
Golay, X, Author
Dickson, J, Author
Shankar, A, Author
Hyare, H, Author
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: Chemical exchange saturation transfer MRI is emerging as a powerful diagnostic tool and has been shown to correlate with glioma tumour grade and molecular genetics. In this study, we aim to investigate whether APT signal is a non-invasive biomarker of Teenage and Young Adult glioma cell proliferation through correlation with 18F-Cho PET SUV as the gold standard. The strong positive correlation found in APT and 18F-Cho PET SUV indirectly demonstrates that APT SI may be a marker of glioma cell proliferation and further demonstrates the potential of APT in the assessment of glioma burden.

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 Dates: 2018-06
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: RegaTHZCAPGDSH2018
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1258 Start / End Page: - Identifier: -