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  Ex vivo continuous Overhauser nuclear dynamic polarization in a SQUID-based ultralow field magnetic resonance imaging system

Fehling, P., Bernard, R., Pohmann, R., Rudolph, M., Kölle, D., Kleiner, R., et al. (2018). Ex vivo continuous Overhauser nuclear dynamic polarization in a SQUID-based ultralow field magnetic resonance imaging system. In Joint Annual Meeting ISMRM-ESMRMB 2018.

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 Creators:
Fehling, P1, 2, Author           
Bernard, R1, 2, Author           
Pohmann, R1, 2, Author           
Rudolph, M1, 2, Author           
Kölle, D, Author
Kleiner, R, Author
Scheffler, K1, 2, Author           
Buckenmaier, K1, 2, Author           
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1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Overhauser Dynamic Nuclear Polarization (ODNP) is a method to achieve continuous hyperpolarization in MR measurements. Here, the polarization of free radicals is transferred to 1H using High Frequency (HF) pulses at the electron Larmor frequency. At UltraLow Fields (ULF) the frequency of the HF pulse lies in the range of several 100 MHz and is able to penetrate large sample volumes, making continuous in vivo ODNP measurements possible. Since conventional Faraday coils are not sensitive enough at ULF, a Superconducting QUantum Interference Device (SQUID) based detector is employed. First ex vivo images using ODNP enhanced MR have been acquired successfully.

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 Dates: 2018-06
 Publication Status: Issued
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 Identifiers: BibTex Citekey: FehlingBPRKKSB2018_2
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
Start-/End Date: 2018-06-16 - 2018-06-21

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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0949 Start / End Page: - Identifier: -