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Abstract:
MRCDI is a novel technique for non-invasive measurement of weak currents in the human head, which is important in several neuroscience applications. Here, we present reliable in-vivo MRCDI measurements in the human brain based on SSFP-FID, yielding an unprecedented accuracy. We demonstrate the destructive influences of stray magnetic fields caused by the current passing through feeding cables, and propose a
correction method. Also, we show inter-individual differences in MRCDI measurements for two different
current profiles, and compare the measurements with simulations based on individualized head models. The
simulations of the current-induced magnetic fields show good agreement with in-vivo brain measurements.