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  Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID)

Göksu, C., Hanson, L., Siebner, H., Ehses, P., Scheffler, K., & Thielscher, A. (2018). Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID). In Joint Annual Meeting ISMRM-ESMRMB 2018.

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 Creators:
Göksu, C, Author           
Hanson, LG, Author
Siebner, HR, Author
Ehses, P1, 2, Author           
Scheffler, K1, 2, Author           
Thielscher, A, Author           
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: MRCDI is a novel technique for non-invasive measurement of weak currents in the human head, which is important in several neuroscience applications. Here, we present reliable in-vivo MRCDI measurements in the human brain based on SSFP-FID, yielding an unprecedented accuracy. We demonstrate the destructive influences of stray magnetic fields caused by the current passing through feeding cables, and propose a correction method. Also, we show inter-individual differences in MRCDI measurements for two different current profiles, and compare the measurements with simulations based on individualized head models. The simulations of the current-induced magnetic fields show good agreement with in-vivo brain measurements.

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 Dates: 2018-06
 Publication Status: Issued
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 Identifiers: BibTex Citekey: GoksuHSEST2018_2
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Place of Event: Paris, France
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Title: Joint Annual Meeting ISMRM-ESMRMB 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0542 Start / End Page: - Identifier: -