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  What We Can and What We Can’t Do with fMRI

Logothetis, N. (2012). What We Can and What We Can’t Do with fMRI. In Society for Neuroscience: 2012 Short Course II MRI and Advanced Imaging in Animals and Humans (pp. 7-14).

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Logothetis, NK1, 2, Author           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Functional activation of the brain can be detected with magnetic resonance imaging (MRI) by directly measuring tissue perfusion, blood-volume changes, or changes in the concentration of oxygen. The latter blood oxygenation level–dependent (BOLD) contrast mechanism (Logothetis, 2003; Logothetis and Wandell, 2004; Logothetis, 2008) is currently the mainstay of human neuroimaging. The interpretation of fMRI signals in brain research, and by extension, the utility of fMRI, critically depends on factors such as signal specificity and spatial and temporal resolution. Signal specificity ensures that the generated maps reflect actual neural changes, whereas spatial and temporal resolution determine our ability to discern the elementary units of the activated networks and the time course of various neural events.

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 Dates: 2012-10
 Publication Status: Published in print
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Title: Society for Neuroscience: 2012 Short Course II MRI and Advanced Imaging in Animals and Humans
Place of Event: New Orleans, LA, USA
Start-/End Date: 2012-10-12

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Title: Society for Neuroscience: 2012 Short Course II MRI and Advanced Imaging in Animals and Humans
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 7 - 14 Identifier: -