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  Fibroblast adhesion on unidirectional polymeric nanofilms

Christophis, C., Sekeroglu, K., Demirel, G., Thome, I., Grunze, M., Demirel, M. C., et al. (2011). Fibroblast adhesion on unidirectional polymeric nanofilms. Biointerphases, 6, 158-163. doi:10.1116/1.3646093.

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 Creators:
Christophis, Christof, Author
Sekeroglu, Koray, Author
Demirel, Gokhan, Author
Thome, Isabel, Author
Grunze, Michael1, Author           
Demirel, Melik C., Author
Rosenhahn, Axel, Author
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1Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_2364731              

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 Abstract: Nanotextured polymeric surfaces with inclined rods reveal highly anisotropic properties concerning wetting and adhesion. In this work, we report on the interaction of fibroblast cells with these highly anisotropic materials. The authors quantified removal of adherent cells from such surfaces by a laminar flow. The critical shear force needed for cell removal from the surface depends on the inclination direction. Based on electron microscopy cross sections we deduce that interactions of cellular filopodia extending into the nanotextured surface are causing the direction depending removal.

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Language(s): eng - English
 Dates: 2011-08-022011-09-142011-10-072011
 Publication Status: Issued
 Pages: 6
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 Table of Contents: -
 Rev. Type: Peer
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Title: Biointerphases
Source Genre: Journal
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Publ. Info: New York, NY : American Vacuum Society
Pages: - Volume / Issue: 6 Sequence Number: - Start / End Page: 158 - 163 Identifier: ISSN: 1559-4106
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000220640_1