English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Localizing Interoceptive Responses via fMRI and Electrophysiology in the Anesthetized Macaque

Hartig, R., Vedoveli, A., Oeltermann, A., Krampe, E., Battal, C., Werner, J., et al. (2018). Localizing Interoceptive Responses via fMRI and Electrophysiology in the Anesthetized Macaque. Poster presented at 11th FENS Forum of Neuroscience, Berlin, Germany.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0001-95F5-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0001-95F6-1
Genre: Poster

Files

show Files

Creators

show
hide
 Creators:
Hartig, R1, 2, Author              
Vedoveli, A1, 2, Author              
Oeltermann, A1, 2, Author              
Krampe, E1, 2, Author              
Battal, C, Author
Werner, J1, 2, Author              
Logothetis, NK1, 2, Author              
Evrard, HC1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: Several well-established methods exist for recording and measuring the underlying signals of the brain; methods such as electrophysiology and fMRI, when taken together, have the capacity to disclose both local and global neuronal activity. Thus, we aimed to employ both techniques to construct a functional model of the insular cortex (IC), a recipient of afferents relaying information from the body’s viscera. For our work, we performed a series of fMRI experiments in the anesthetized macaque (n = 11), where we measured the responses to interoceptive stimulation (e.g. lower gastrointestinal tract, cutaneous temperature, auricular vagus nerve branch, gustation); and exploited the gross functional anatomical localizations (area: 4mm2) of these functions to establish a foundation for subsequent electrophysiological sampling (area: 1mm2, n = 4) across the IC. Using these methods, our results reveal a topographic organization of interoceptive processing and highlight its functional similarity to that of the human insular cortex. As localized by fMRI and electrophysiology, two anatomically discrete areas along the mid-anterior dorsal IC were responsive to oral and gustatory sensations. However, our fMRI results disclosed lower gastrointestinal activity to be predominantly correlated with the ventral anterior IC. Such results already depict a select arrangement of multi-modal inputs within the macaque insula. As the IC is the primary cortical recipient of interoceptive inputs, the manner in which this information is organized may disclose how these inputs are relayed to form a conscious percept of the body’s physiological state, contribute to emotional embodiment, and provide top-down influence on bodily function.

Details

show
hide
Language(s):
 Dates: 2018-07
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: -
 Degree: -

Event

show
hide
Title: 11th FENS Forum of Neuroscience
Place of Event: Berlin, Germany
Start-/End Date: 2018-07-07 - 2018-07-11

Legal Case

show

Project information

show

Source 1

show
hide
Title: 11th FENS Forum of Neuroscience
Source Genre: Proceedings
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: 37226 Start / End Page: - Identifier: -