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Abstract:
The energy supply in cells is provided by molecules that contain phosphorus. Especially phosphocreatine (PCr) and adenosine triphosphate (ATP) are phosphorus metabolites that carry the energy needed for most processes in the brain, muscles and other organs. Magnetic Resonance Spectroscopy has the potential to quantitatively detect these substances in living subjects noninvasively. For routine applications, however, 31P MRS suffers from its low SNR due to the low concentration of 31P metabolites and the reduced Larmor frequency compared to protons. Using an ultra-high field of 9.4 T for 31P MRS is expected to yield significantly higher SNR and thus has the potential to make this technique a valuable tool in clinical and scientific examinations.
