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Abstract:
Inhalation of fine particulate matter can lead to the formation of ra-
dicals and H
2
O
2
in epithelial lung fluid (ELF), induce oxidative stress and
cause adverse health effects. 1,2 Quinones are important redox-active
components of fine particulate matter that may be essential for the
generation of H
2
O
2
and oxidative stress. We investigated the H
2
O
2
yield of
9,10 anthraquinone, 1,2- and 1,4- naphthoquinones in surrogate lung fluid
(SLF). We found that 9,10 anthraquinone has a relatively low H
2
O
2
yield in
SLF, whereas 1,2- and 1,4- naphthoquinone exhibit high and strongly pH-
dependent H
2
O
2
yields.
E-mail address: a.filippi@mpic.de
References
1:Pope III and Dockery, Journal of the air and waste management as-
sociation 2006, 56, (6), 709–742.
2:Lakey, et al., Scientific reports 2016, 6, 3291
