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  Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016

Olschewski, A., Berghausen, E. M., Eichstaedt, C. A., Fleischmann, B. K., Gruenig, E., Gruenig, G., et al. (2016). Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 141, S4-+. doi:10.1055/s-0042-114520.

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 Creators:
Olschewski, A., Author
Berghausen, E. M., Author
Eichstaedt, C. A., Author
Fleischmann, B. K., Author
Gruenig, E., Author
Gruenig, G., Author
Hansmann, G., Author
Harbaum, L., Author
Hennigs, J. K., Author
Jonigk, D., Author
Kuebler, W. M., Author
Kwapiszewska, G., Author
Pullamsetti, Soni Savai1, Author              
Stacher, E., Author
Weissmann, N., Author
Wenzel, D., Author
Schermuly, R. T., Author
Affiliations:
1Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, Max Planck Society, ou_2591698              

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Free keywords: ARTERIAL-HYPERTENSION; RIGHT VENTRICLE; ION CHANNELS; HUMAN LUNG; VASOCONSTRICTION; CIRCULATION; HYPOXIA; DEFECTS; CONTRIBUTES; DYSFUNCTIONGeneral & Internal Medicine; inflammation; metabolism; BMPR2; FoxO1; KCNK3; TASK-1;
 Abstract: The 2015 European Guidelines on Diagnosis and Treatment of Pulmonary Hypertension (PH) are also valid for Germany. While the guidelines contain detailed recommendations regarding clinical aspects of pulmonary arterial hypertension (PAH) and other forms of PH, they contain only a relatively short paragraph on novel findings on the pathobiology, pathology, and genetics. However, these are of great importance for our understanding of this complex disease both from a clinical and scientific point of view, and they are essential for the development of novel treatment strategies. To this end, a number of current data are relevant, prompting a detailed commentary to the guidelines, and the consideration of new scientific data. In June 2016, a Consensus Conference organized by the PH working groups of the German Society of Cardiology (DGK), the German Society of Respiratory Medicine (DGP) and the German Society of Pediatric Cardiology (DGPK) was held in Cologne, Germany. This conference aimed to solve practical and controversial issues surrounding the implementation of the European Guidelines in Germany. To this end, a number of working groups was initiated, one of which was specifically dedicated to the pathobiology, pathology and genetics of PH. This article summarizes the results and recommendations of this working group.

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Language(s): deu - German
 Dates: 2016
 Publication Status: Published in print
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 000386913900002
DOI: 10.1055/s-0042-114520
 Degree: -

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Title: DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT
Source Genre: Journal
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Affiliations:
Publ. Info: RUDIGERSTR 14, D-70469 STUTTGART, GERMANY : GEORG THIEME VERLAG KG
Pages: - Volume / Issue: 141 Sequence Number: - Start / End Page: S4 - + Identifier: ISSN: 0012-0472