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  Mathematical Modeling of the Neuronal Processes in Sugar Addiction

Almeida, A., Celaymanian, H., Seel, N., Zak, B., & Noori, H. (2011). Mathematical Modeling of the Neuronal Processes in Sugar Addiction.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0001-BCA2-4 Version Permalink: http://hdl.handle.net/21.11116/0000-0001-BCA3-3
Genre: Poster

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Almeida, A, Author
Celaymanian, H, Author
Seel, N, Author
Zak, B, Author
Noori, HR1, Author              
Affiliations:
1Interdisciplinary Center for Scientific Computing, University of Heidelberg, ou_persistent22              

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 Abstract: It has already been demonstrated that the body responds to enhanced intake of sugar and is conducive to a natural form of addiction. There are substantial neurochemical changes in the brain (especially dopamine and acetylcholine systems) similar to other addictive drugs. A mathematical model comprised by a system of delayed leaky integrate-and-re equations is established to simulate the effects of sugar on a reward-circuitry. Simulations with Neuron suggest agreement with the neurobiological hypotheses of hyperactivity of neural systems due to binge sugar intake.

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 Dates: 2011-02
 Publication Status: Published in print
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 Identifiers: DOI: 10.1038/npre.2011.5546.2
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Title: Nature Precedings
Source Genre: Journal
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