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  Organ Function as a Modulator of Organ Formation: Lessons from Zebrafish

Collins, M. M., & Stainier, D. Y. (2016). Organ Function as a Modulator of Organ Formation: Lessons from Zebrafish. ESSAYS ON DEVELOPMENTAL BIOLOGY, PT B, 417-433. doi:10.1016/bs.ctdb.2015.10.017.

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Genre: Journal Article

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 Creators:
Collins, Michelle M.1, Author              
Stainier, Didier Y.R.1, Author              
Affiliations:
1Developmental Genetics, Max Planck Institute for Heart and Lung Research, Max Planck Society, ou_2591697              

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Free keywords: FLUID SHEAR-STRESS; VASCULAR ENDOTHELIAL-CELLS; HEART TUBE; CARDIOVASCULAR DEVELOPMENT; CARDIAC CONDUCTION; VALVE DEVELOPMENT; EPIGENETIC FACTOR; FLOW; MORPHOGENESIS; EXPRESSIONDevelopmental Biology;
 Abstract: Organogenesis requires an intricate balance between cell differentiation and tissue growth to generate a complex and fully functional organ. However, organogenesis is not solely driven by genetic inputs, as the development of several organ systems requires their own functionality. This theme is particularly evident in the developing heart as progression of cardiac development is accompanied by increased and altered hemodynamic forces. In the absence or disruption of these forces, heart development is abnormal, suggesting that the heart must sense these changes and respond appropriately. Here, we discuss concepts of how embryonic heart function contributes to heart development using lessons learned mostly from studies in zebrafish.

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Language(s): eng - English
 Dates: 2016
 Publication Status: Published in print
 Pages: 17
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Degree: -

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Title: ESSAYS ON DEVELOPMENTAL BIOLOGY, PT B
  Alternative Title : Curr. Top. Dev. Biol.
  Alternative Title : CURR TOP DEV BIOL
Source Genre: Proceedings
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Affiliations:
Publ. Info: 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA : ELSEVIER ACADEMIC PRESS INC
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 417 - 433 Identifier: ISSN: 0070-2153
ISBN: 978-0-12-801616-9; 978-0-12-801382-3

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Title: Current Topics in Developmental Biology
  Alternative Title : CURR TOP DEV BIOL
  Alternative Title : Curr. Top. Dev. Biol.
Source Genre: Series
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Publ. Info: -
Pages: - Volume / Issue: 117 Sequence Number: - Start / End Page: - Identifier: ISSN: 0070-2153