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  Visualizing biochemical activities in living cells through chemistry.

Reymond, L., Lukinavicius, G., Umezawa, K., Maurel, D., Brun, M. A., Masharina, A., et al. (2011). Visualizing biochemical activities in living cells through chemistry. Chimia, 65(11), 868-871. doi:10.2533/chimia.2011.868.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0001-DED3-7 Version Permalink: http://hdl.handle.net/21.11116/0000-0001-DED6-4
Genre: Journal Article

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2628646.pdf (Publisher version), 780KB
 
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 Creators:
Reymond, L., Author
Lukinavicius, G.1, Author              
Umezawa, K., Author
Maurel, D., Author
Brun, M. A., Author
Masharina, A., Author
Bojkowska, K., Author
Mollwitz, B., Author
Schena, A., Author
Griss, R., Author
Johnsson, K., Author
Affiliations:
1Laboratory of Chromatin Labeling and Imaging, Max Planck Institute for Biophysical Chemistry, Max Planck Society, ou_2616691              

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 Abstract: The development of molecular probes to visualize cellular processes is an important challenge in chemical biology. One possibility to create such cellular indicators is based on the selective labeling of proteins with synthetic probes in living cells. Over the last years, our laboratory has developed different labeling approaches for monitoring protein activity and for localizing synthetic probes inside living cells. In this article, we review two of these labeling approaches, the SNAP-tag and CLIP-tag technologies, and their use for studying cellular processes.

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Language(s): eng - English
 Dates: 2011-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.2533/chimia.2011.868
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Title: Chimia
Source Genre: Journal
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Pages: - Volume / Issue: 65 (11) Sequence Number: - Start / End Page: 868 - 871 Identifier: -