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  New S-adenosyl-L-methionine analogs with extended activated groups for transfer by methyltransferases

Weinhold, E., Dalhoff, S., Klimasauskas, S., & Lukinavicius, G.(2006). New S-adenosyl-L-methionine analogs with extended activated groups for transfer by methyltransferases.

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Weinhold, E., Author
Dalhoff, S., Author
Klimasauskas, S., Author
Lukinavicius, G.1, Author              
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1Laboratory of Chromatin Labeling and Imaging, Max Planck Institute for Biophysical Chemistry, Max Planck Society, ou_2616691              

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 Abstract: S-Adenosyl-L-methionine analogs of formula (I) wherein R comprises a carbon-carbon double bond, carbon-oxygen double bond, carbon-sulfur double bond, carbon-nitrogen double bond, a carbon-carbon triple bond, carbon-nitrogen triple bond or an aromatic carbocyclic or heterocyclic system in ß-position to the sulfonium center, X- is an organic or inorganic anion carrying one or more negative charges, Z is -CR1R2-, -O-, -S- or -NR3- and R1, R2 and R3 are independently selected from H, D and C1-C12alkyl.

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 Dates: 2006-04-132006-10-19
 Publication Status: Published online
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 Identifiers: Patent Nr.: WO002006108678A2
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