English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Cell permeable fluorescent dye
Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0001-ECB4-A Version Permalink: http://hdl.handle.net/21.11116/0000-0002-0DF4-D
Genre: Patent

Files

show Files
hide Files
:
2632407.pdf (Publisher version), 3MB
Name:
2632407.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Umezawa, K., Author
Lukinavicius, G.1, Author              
Johnsson, K., Author
Affiliations:
1Laboratory of Chromatin Labeling and Imaging, Max Planck Institute for Biophysical Chemistry, Max Planck Society, ou_2616691              

Content

show
hide
Free keywords: -
 Abstract: The invention pertains to a near-infrared fluorescent dye that is cell permeable and can be attached to selected proteins in living cells. The dye has the general formula (I) or its or its corresponding spirolactone (II) wherein Y is chosen from the group consisting of Si, Ge and Sn; R0 is -COO- or COOH; R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15 and R16 are substituents, including hydrogen, independently from each other. The dye (i) absorbs and emits light at wavelengths above 600 nm; (ii) possesses high photostability; (iii) has high extinction coefficients and high quantum yields; (iv) can be derivatized with different molecules; and (v) is membrane-permeable and shows mini¬ mal background binding to biomolecules and biomolecular structures.

Details

show
hide
Language(s):
 Dates: 2011-08-262013-03-07
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: Patent Nr.: WO 2013/029650 A1
 Degree: -

Event

show

Legal Case

show

Project information

show

Source

show