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  Simultaneous multislice triple‐echo steady‐state (SMS‐TESS) T1, T2, PD, and off‐resonance mapping in the human brain

Heule, R., Celikanin, Z., Kozerke, S., & Bieri, O. (2018). Simultaneous multislice triple‐echo steady‐state (SMS‐TESS) T1, T2, PD, and off‐resonance mapping in the human brain. Magnetic Resonance in Medicine, 80(3), 1088-1100. doi:10.1002/mrm.27126.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0002-445F-8 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-4460-5
Genre: Journal Article

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Heule, R1, Author              
Celikanin , Z, Author
Kozerke, S, Author
Bieri, O, Author
Affiliations:
1University Hospital Basel, ou_persistent22              

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 Abstract: Purpose To investigate the ability of simultaneous multislice triple‐echo steady‐state (SMS‐TESS) imaging to provide quantitative maps of multiple tissue parameters, i.e., longitudinal and transverse relaxation times (T1 and T2), proton density (PD), and off‐resonance (ΔB0), in the human brain at 3T from a single scan. Methods TESS acquisitions were performed in 2D mode to reduce motion sensitivity and accelerated by an SMS excitation scheme (CAIPIRINHA) with SENSE reconstruction. SMS‐acceleration factors (R) of 2 and 4 were evaluated. The in vitro and in vivo validation process included standard reference scans to analyze the accuracy of T1, T2, and ΔB0 estimates, as well as single‐slice TESS measurements. Results For R = 2, the quantification of T1, T2, PD, and ΔB0 was overall reliable with marginal noise enhancement. T1 and T2 values were in good agreement with the reference measurements and single‐slice TESS. For R = 4, the agreement of ΔB0 with the standard reference was excellent and the determination of T1, T2, and PD was reproducible; however, increased variations in T1 and T2 values with respect to single‐slice TESS were observed. Conclusion SMS‐TESS has shown potential to offer rapid simultaneous T1, T2, PD, and ΔB0 mapping of human brain tissues.

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 Dates: 2018-09
 Publication Status: Published in print
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 Identifiers: DOI: 10.1002/mrm.27126
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 80 (3) Sequence Number: - Start / End Page: 1088 - 1100 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149