English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The reciprocal relation between sleep and memory in infancy: Memory-dependent adjustment of sleep spindles and spindle-dependent improvement of memories

Friedrich, M., Mölle, M., Friederici, A. D., & Born, J. (2019). The reciprocal relation between sleep and memory in infancy: Memory-dependent adjustment of sleep spindles and spindle-dependent improvement of memories. Developmental Science, 22(2): e12743. doi:10.1111/desc.12743.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0002-5284-C Version Permalink: http://hdl.handle.net/21.11116/0000-0003-926E-D
Genre: Journal Article

Files

show Files
hide Files
:
Friedrich_Mölle_2018.pdf (Publisher version), 688KB
Name:
Friedrich_Möller_2018.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Friedrich, Manuela1, 2, Author              
Mölle, Matthias3, Author
Friederici, Angela D.1, Author              
Born, Jan4, Author
Affiliations:
1Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634551              
2Institute of Psychology, Humboldt University Berlin, Germany, ou_persistent22              
3Center of Brain, Behavior and Metabolism (CBBM), University of Lübeck, Germany, ou_persistent22              
4Institute of Medical Psychology and Behavioral Neurobiology, Eberhard Karls University Tübingen, Germany, ou_persistent22              

Content

show
hide
Free keywords: consolidation; generalization; learning; memory; sleep; sleep spindles
 Abstract: Sleep spindle activity in infants supports their formation of generalized memories during sleep, indicating that specific sleep processes affect the consolidation of memories early in life. Characteristics of sleep spindles depend on the infant's developmental state and are known to be associated with trait-like factors such as intelligence. It is, however, largely unknown which state-like factors affect sleep spindles in infancy. By varying infants' wake experience in a within-subject design, here we provide evidence for a learning- and memory-dependent modulation of infant spindle activity. In a lexical-semantic learning session before a nap, 14- to 16-month-old infants were exposed to unknown words as labels for exemplars of unknown object categories. In a memory test on the next day, generalization to novel category exemplars was tested. In a nonlearning control session preceding a nap on another day, the same infants heard known words as labels for exemplars of already known categories. Central-parietal fast sleep spindles increased after the encoding of unknown object-word pairings compared to known pairings, evidencing that an infant's spindle activity varies depending on its prior knowledge for newly encoded information. Correlations suggest that enhanced spindle activity was particularly triggered, when similar unknown pairings were not generalized immediately during encoding. The spindle increase triggered by previously not generalized object-word pairings, moreover, boosted the formation of generalized memories for these pairings. Overall, the results provide first evidence for a fine-tuned regulation of infant sleep quality according to current consolidation requirements, which improves the infant long-term memory for new experiences.

Details

show
hide
Language(s): eng - English
 Dates: 2017-12-042018-08-242018-08-302019-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1111/desc.12743
PMID: 30160012
Other: Epub 2018
 Degree: -

Event

show

Legal Case

show

Project information

show hide
Project name : -
Grant ID : FR 1336/2‐1 ; FR 1336/2‐2
Funding program : -
Funding organization : Deutsche Forschungsgemeinschaft (DFG)

Source 1

show
hide
Title: Developmental Science
  Other : Dev. Sci.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Oxford, UK : Blackwell
Pages: - Volume / Issue: 22 (2) Sequence Number: e12743 Start / End Page: - Identifier: ISSN: 1363-755X
CoNE: https://pure.mpg.de/cone/journals/resource/963018343339