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  Partial genomic survival of cave bears in living brown bears

Barlow, A., Cahill, J. A., Hartmann, S., Theunert, C., Xenikoudakis, G., Fortes, G. G., et al. (2018). Partial genomic survival of cave bears in living brown bears. Nature Ecology & Evolution, 2, 1563-1570. doi:10.1038/s41559-018-0654-8.

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 Urheber:
Barlow, Axel, Autor
Cahill, James A., Autor
Hartmann, Stefanie, Autor
Theunert, Christoph1, Autor           
Xenikoudakis, Georgios, Autor
Fortes, Gloria G., Autor
Paijmans, Johanna L. A., Autor
Rabeder, Gernot, Autor
Frischauf, Christine, Autor
Grandal-d’Anglade, Aurora, Autor
García-Vázquez, Ana, Autor
Murtskhvaladze, Marine, Autor
Saarma, Urmas, Autor
Anijalg, Peeter, Autor
Skrbinšek, Tomaž, Autor
Bertorelle, Giorgio, Autor
Gasparian, Boris, Autor
Bar-Oz, Guy, Autor
Pinhasi, Ron, Autor
Slatkin, Montgomery, Autor
Dalén, Love, AutorShapiro, Beth, AutorHofreiter, Michael, Autor mehr..
Affiliations:
1Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_1497672              

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 Zusammenfassung: Although many large mammal species went extinct at the end of the Pleistocene epoch, their DNA may persist due to past episodes of interspecies admixture. However, direct empirical evidence of the persistence of ancient alleles remains scarce. Here, we present multifold coverage genomic data from four Late Pleistocene cave bears (Ursus spelaeus complex) and show that cave bears hybridized with brown bears (Ursus arctos) during the Pleistocene. We develop an approach to assess both the directionality and relative timing of gene flow. We find that segments of cave bear DNA still persist in the genomes of living brown bears, with cave bears contributing 0.9 to 2.4% of the genomes of all brown bears investigated. Our results show that even though extinction is typically considered as absolute, following admixture, fragments of the gene pool of extinct species can survive for tens of thousands of years in the genomes of extant recipient species.

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Sprache(n): eng - English
 Datum: 2018-08-272018-10
 Publikationsstatus: Erschienen
 Seiten: 10
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1038/s41559-018-0654-8
 Art des Abschluß: -

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Titel: Nature Ecology & Evolution
Genre der Quelle: Zeitschrift
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Affiliations:
Ort, Verlag, Ausgabe: London : Nature Publishing Group
Seiten: - Band / Heft: 2 Artikelnummer: - Start- / Endseite: 1563 - 1570 Identifikator: ISSN: 2397-334X
CoNE: https://pure.mpg.de/cone/journals/resource/2397-334X