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  Effects of resveratrol on cognitive functions

Huhn, S., & Witte, A. V. (2017). Effects of resveratrol on cognitive functions. In R. R. Watson (Ed.), Nutrition and functional foods for healthy aging (pp. 283 -292 ). London: Elsevier. doi:10.1016/B978-0-12-805376-8.00024-1.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0002-9D61-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-9D62-F
Genre: Book Chapter

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 Creators:
Huhn, Sebastian1, 2, Author              
Witte, A. Veronica1, 2, Author              
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2University of Leipzig, Germany, ou_persistent22              

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 Abstract: Resveratrol (RSV) is a naturally occurring polyphenol found in berries, grapes, red wine, and nuts. Based on numerous animal and human studies, it has been suggested as a possible candidate for the treatment of cardiovascular impairments, metabolic dysfunctions, and neurodegenerative diseases. Beyond that, research has started to focus on its influence on cognitive functions and animal studies have described RSV’s beneficial effects on brain structure and function. The first controlled studies in humans reported the beneficial effects of RSV administration with regard to cognitive functions, especially in older populations. Possible underlying mechanisms of RSV range from antioxidant and antiinflammatory actions to the activation of sirtuins and neuroprotective properties. Future studies should now address previous limitations such as flaws in the study design and focus on translating findings from animals to humans and eventually strengthen the hypothesis that RSV could help maintain cognitive health until old age. This chapter summarizes what is known about the effects of RSV on health outcomes with a focus on cognitive functions and possible underlying mechanisms. In addition, we discuss limitations and challenges of previous studies as well as future perspectives in RSV research.

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Language(s): eng - English
 Dates: 2017-02-102017
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Degree: -

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Title: Nutrition and functional foods for healthy aging
Source Genre: Book
 Creator(s):
Watson, Ronald Ross , Editor
Affiliations:
-
Publ. Info: London : Elsevier
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 283 - 292 Identifier: ISBN: 978-0-12-805376-8