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  The impact of structural biology on alkaloid biosynthesis research

Panjikar, S., Stoeckigt, J., O'Connor, S. E., & Warzecha, H. (2012). The impact of structural biology on alkaloid biosynthesis research. Natural Product Reports, 29(10), 1176-1200. doi:10.1039/c2np20057k.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0002-B236-8 Version Permalink: https://hdl.handle.net/21.11116/0000-0009-3D49-2
Genre: Journal Article

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SOC035.pdf (Publisher version), 3MB
 
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 Creators:
Panjikar, Santosh1, Author
Stoeckigt, Joachim1, Author
O'Connor, Sarah E.1, Author           
Warzecha, Heribert1, Author
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1external, ou_persistent22              

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Free keywords: BERBERINE BRIDGE ENZYME; X-RAY-ANALYSIS; MACROMOLECULAR CRYSTALLOGRAPHy BEAMLINES; POLYNEURIDINE ALDEHYDE ESTERASE; SPENGLER CATALYZING ENZYME; PROTEIN-STRUCTURE SOLUTION; SITE-DIRECTED MUTAGENESIS; COVALENTLY ATTACHED FAD; 1ST COMMITTED STEP; SHAKE-AND-BAKEBiochemistry & Molecular Biology; Pharmacology & Pharmacy; Chemistry;
 Abstract: In the recent past, macromolecular crystallography has gone through substantial methodological and technological development. The purpose of this review is to provide a general overview of structural biology and its impact on enzyme structure/function analysis and illustrate how it is modifying the focus of research relevant to alkaloid biosynthesis.

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Language(s): eng - English
 Dates: 2012
 Publication Status: Issued
 Pages: 25
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: Other: SOC035
DOI: 10.1039/c2np20057k
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Title: Natural Product Reports
  Abbreviation : Nat. Prod. Rep.
Source Genre: Journal
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Publ. Info: Cambridge, England : Royal Society of Chemistry
Pages: - Volume / Issue: 29 (10) Sequence Number: - Start / End Page: 1176 - 1200 Identifier: ISSN: 0265-0568
CoNE: https://pure.mpg.de/cone/journals/resource/110978977979506