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  Quantitative Magnetization Transfer Imaging in Postmortem Brain at 3T Using BSSFP

Soellinger, M., Langkammer, C., Seifert-Held, T., Krebs, N., Gloor, M., Scheurer, E., et al. (2010). Quantitative Magnetization Transfer Imaging in Postmortem Brain at 3T Using BSSFP. Poster presented at ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden.

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Soellinger, M, Author
Langkammer, C, Author
Seifert-Held, T, Author
Krebs, N, Author
Gloor, M, Author
Scheurer, E, Author
Scheffler, K1, Author           
Fazekas, F, Author
Ropele, S, Author
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1University Hospital Basel, ou_persistent22              

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 Abstract: A crucial issue in determining quantitative magnetization transfer (qMT) parameters using balanced steady state free precession (bSSFP) is the estimation of the on-resonant singularity of the superlorentzian absorption line shape G0. We present an empirical G0 calibration method for postmortem in-situ brain scans at 3T using cross-linked BSA (bovine serum albumin) probes. For the investigated temperature range from 6-20°C G0 resulted in 2.0*10-5. First qMT results of three postmortem in-situ brain scans revealed decreased bound pool size ratios f in white matter compared to in-vivo scans.

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 Dates: 2010-05
 Publication Status: Issued
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Title: ISMRM-ESMRMB Joint Annual Meeting 2010
Place of Event: Stockholm, Sweden
Start-/End Date: 2010-05-01 - 2010-05-07

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Title: ISMRM-ESMRMB Joint Annual Meeting 2010
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 5144 Start / End Page: - Identifier: -