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  Target Engagement of Small Molecules: Thermal Profiling Approaches on Different Levels

Reckzeh, E. S., Brockmeyer, A., Metz, M., Waldmann, H., & Janning, P. (2018). Target Engagement of Small Molecules: Thermal Profiling Approaches on Different Levels. In Systems Chemical Biology; Methods in Molecular Biology, Vol. 1888 (pp. 73-98). New York, NY: Springer Verlag Humana Press.

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 Creators:
Reckzeh, Elena S.1, Author           
Brockmeyer, Andreas1, Author           
Metz, Malte1, Author           
Waldmann, Herbert1, Author           
Janning, Petra1, Author           
Affiliations:
1Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753290              

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Free keywords: (Off)target; Cellular thermal shift assay (CETSA); Immunoblot; Nano-LC-MS/MS; Proteomics; Target engagement; Target identification; Thermal proteome profiling (TPP)
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Language(s): eng - English
 Dates: 2018-12
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Internal
 Identifiers: DOI: 10.1007/978-1-4939-8891-4_4
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Title: Systems Chemical Biology; Methods in Molecular Biology, Vol. 1888
Source Genre: Book
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Publ. Info: New York, NY : Springer Verlag Humana Press
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 73 - 98 Identifier: ISBN: 978-1-4939-8890-7