Target Engagement of Small Molecules: Thermal Profiling Approaches on Different 
Levels

Reckzeh, Elena S.; Brockmeyer, Andreas; Metz, Malte; Waldmann, Herbert; Janning, Petra

doi:10.1007/978-1-4939-8891-4_4

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Target Engagement of Small Molecules: Thermal Profiling Approaches on Different Levels

Reckzeh, E. S., Brockmeyer, A., Metz, M., Waldmann, H., & Janning, P. (2018). Target Engagement of Small Molecules: Thermal Profiling Approaches on Different Levels. In Systems Chemical Biology; Methods in Molecular Biology, Vol. 1888 (pp. 73-98). New York, NY: Springer Verlag Humana Press.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0002-A6B5-6 Version Permalink: https://hdl.handle.net/21.11116/0000-0002-A6B7-4

Genre: Book Chapter

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Creators:
Reckzeh, Elena S.¹, Author
Brockmeyer, Andreas¹, Author
Metz, Malte¹, Author
Waldmann, Herbert¹, Author
Janning, Petra¹, Author

Affiliations:
1Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753290

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Free keywords: (Off)target; Cellular thermal shift assay (CETSA); Immunoblot; Nano-LC-MS/MS; Proteomics; Target engagement; Target identification; Thermal proteome profiling (TPP)

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Language(s): eng - English

Dates: Date issued: 2018-12

Publication Status: Issued

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Rev. Type: Internal

Identifiers: DOI: 10.1007/978-1-4939-8891-4_4

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Title: Systems Chemical Biology; Methods in Molecular Biology, Vol. 1888

Source Genre: Book

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Publ. Info: New York, NY : Springer Verlag Humana Press

Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 73 - 98 Identifier: ISBN: 978-1-4939-8890-7