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  Interaction of DNA with DNA‐binding proteins: the characterization of protein HD from Escherichia coli and its nucleic acid complexes

Berthold, V., & Geider, K. (1976). Interaction of DNA with DNA‐binding proteins: the characterization of protein HD from Escherichia coli and its nucleic acid complexes. European Journal of Biochemistry, 71(2), 443-449. doi:10.1111/j.1432-1033.1976.tb11132.x.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0002-AE02-8 Version Permalink: https://hdl.handle.net/21.11116/0000-000A-2A40-F
Genre: Journal Article

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EurJBiochem_71_1976_443.pdf (Any fulltext), 545KB
 
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https://febs.onlinelibrary.wiley.com/doi/epdf/10.1111/j.1432-1033.1976.tb11132.x (Any fulltext)
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https://doi.org/10.1111/j.1432-1033.1976.tb11132.x (Any fulltext)
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 Creators:
Berthold, Verena, Author
Geider, Klaus1, Author           
Affiliations:
1Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              

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 Abstract: DNA‐binding protein HD with a monomer molecular weight of 9000 was isolated from Escherichia coli cells. The protein occurs as a tetramer under native conditions and binds to single and double‐stranded DNA and also to RNA. DNA complexed with protein HD is a poor template for DNA synthesis by E. coli polymerase I, II or III holoenzyme. Exonuclease III is hindered in degrading HD‐protein‐covered double‐stranded DNA, whereas exonuclease I can digest complexed single‐stranded DNA. Transcription is slightly stimulated in the presence of protein HD.

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Language(s): eng - English
 Dates: 1976-06-291976-08-231976-12
 Publication Status: Issued
 Pages: 7
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1111/j.1432-1033.1976.tb11132.x
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Title: European Journal of Biochemistry
Source Genre: Journal
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Publ. Info: Berlin : Published by Springer-Verlag on behalf of the Federation of European Biochemical Societies
Pages: - Volume / Issue: 71 (2) Sequence Number: - Start / End Page: 443 - 449 Identifier: ISSN: 0014-2956
CoNE: https://pure.mpg.de/cone/journals/resource/111097776606040