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  A DNA fragment from the origin of single-strand to double-strand DNA replication of bacteriophage fd

Schaller, H., Uhlmann, A., & Geider, K. (1976). A DNA fragment from the origin of single-strand to double-strand DNA replication of bacteriophage fd. Proceedings of the National Academy of Sciences of the United States of America, 73(1), 49-53. doi:10.1073/pnas.73.1.49.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0002-B002-4 Version Permalink: https://hdl.handle.net/21.11116/0000-0002-B003-3
Genre: Journal Article

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 Creators:
Schaller, Heinz, Author
Uhlmann, A.1, Author           
Geider, Klaus2, Author           
Affiliations:
1Max Planck Institute for Medical Research, Max Planck Society, ou_1125545              
2Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              

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 Abstract: A specific complex is formed between fd DNA, Escherichia coli DNA unwinding protein, and RNA polymerase (EC 2.7.7.6; nucleosidetriphosphate:RNA nucleotidyltransferase) during the first steps in the conversion of the single-stranded viral DNA to the double-stranded replicative form. In this complex a unique DNA fragment of about 120 nucleotides is protected against nuclease digestion. Both the requirements for its isolation and its position on the map of the phage genome indicate that the fragment contains the origin of single-strand to double-strand DNA replication. The isolated DNA fragment possesses double-strand-like characteristics, which protect it from being covered by the DNA unwinding protein and thus indirectly positions the RNA polymerase to the origin of replication.

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Language(s): eng - English
 Dates: 1975-10-081976-01-01
 Publication Status: Issued
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1073/pnas.73.1.49
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Title: Proceedings of the National Academy of Sciences of the United States of America
  Other : Proc. Acad. Sci. USA
  Other : Proc. Acad. Sci. U.S.A.
  Other : Proceedings of the National Academy of Sciences of the USA
  Abbreviation : PNAS
Source Genre: Journal
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Publ. Info: Washington, D.C. : National Academy of Sciences
Pages: - Volume / Issue: 73 (1) Sequence Number: - Start / End Page: 49 - 53 Identifier: ISSN: 0027-8424
CoNE: https://pure.mpg.de/cone/journals/resource/954925427230