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  mGene.web: a web service for accurate computational gene finding

Schweikert, G., Behr, J., Zien, A., Zeller, G., Ong, C., Sonnenburg, S., et al. (2009). mGene.web: a web service for accurate computational gene finding. Nucleic Acids Research (London), 37(Supplement 2), W312-W316. doi:10.1093/nar/gkp479.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0002-BF7E-B Version Permalink: http://hdl.handle.net/21.11116/0000-0002-BF7F-A
Genre: Journal Article

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Schweikert, G1, 2, Author              
Behr, J2, 3, Author              
Zien, A2, 3, Author              
Zeller, G1, 2, Author              
Ong, CS3, 4, Author              
Sonnenburg, S2, 3, Author              
Rätsch, G2, 4, Author              
Affiliations:
1Max Planck Institute for Developmental Biology, Max Planck Society, Max-Planck-Ring 5, 72076 Tübingen, DE, ou_2421691              
2Friedrich Miescher Laboratory, Max Planck Society, Max-Planck-Ring 9, 72076 Tübingen, DE, ou_2575692              
3Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
4Department Empirical Inference, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497795              

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 Abstract: We describe mGene.web, a web service for the genome-wide prediction of protein coding genes from eukaryotic DNA sequences. It offers pre-trained models for the recognition of gene structures including untranslated regions in an increasing number of organisms. With mGene.web, users have the additional possibility to train the system with their own data for other organisms on the push of a button, a functionality that will greatly accelerate the annotation of newly sequenced genomes. The system is built in a highly modular way, such that individual components of the framework, like the promoter prediction tool or the splice site predictor, can be used autonomously. The underlying gene finding system mGene is based on discriminative machine learning techniques and its high accuracy has been demonstrated in an international competition on nematode genomes. mGene.web is available at http://www.mgene.org/web, it is free of charge and can be used for eukaryotic genomes of small to moderate size (several hundred Mbp).

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 Dates: 2009-07
 Publication Status: Published in print
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 Identifiers: DOI: 10.1093/nar/gkp479
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Title: Nucleic Acids Research (London)
  Other : Nucleic Acids Res
Source Genre: Journal
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Publ. Info: Oxford : Oxford University Press
Pages: - Volume / Issue: 37 (Supplement 2) Sequence Number: - Start / End Page: W312 - W316 Identifier: ISSN: 0305-1048
CoNE: https://pure.mpg.de/cone/journals/resource/110992357379342