ausblenden:
Schlagwörter:
Oxalate; Sarcoplasmic Reticulum; Influx Rate; High Unsaturated Fatty Acid; Phosphatide Content
Zusammenfassung:
In uremia, the membrane composition of the SR is altered: the ATPase carrier complex decreases, the phosphatide, but not the cholesterol content of the membranes decreases and the fatty acid pattern changes. All these lipid changes are known to affect the kinetic properties of lipoprotein enzymes (6, 7, 8). In uremia the altered lipoprotein interactions of the membrane are paralleled by an impairment of nearly all kinetic parameters of the SR.
