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  Active Ca transport of sarcoplasmic reticulum during experimental uremia

Heimberg, K.-W., MATTHEWS, C., RITZ, E., Augustin, J., & Hasselbach, W. (1976). Active Ca transport of sarcoplasmic reticulum during experimental uremia. European Journal of Biochemistry, 61(1), 207-213. doi:10.1111/j.1432-1033.1976.tb10013.x.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0002-C3FB-7 Version Permalink: https://hdl.handle.net/21.11116/0000-000A-314B-B
Genre: Journal Article

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EurJBiochem_61_1976_207.pdf (Any fulltext), 615KB
 
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https://febs.onlinelibrary.wiley.com/doi/epdf/10.1111/j.1432-1033.1976.tb10013.x (Any fulltext)
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https://doi.org/10.1111/j.1432-1033.1976.tb10013.x (Any fulltext)
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 Creators:
Heimberg, K.-W.1, Author           
MATTHEWS , Clifford, Author
RITZ , Eberhard, Author
Augustin, Jan1, Author           
Hasselbach, Wilhelm2, Author           
Affiliations:
1Max Planck Institute for Medical Research, Max Planck Society, ou_1125545              
2Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              

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 Abstract: The Ca‐transport system of sarcoplasmic vesicles of rabbits is altered by experimental uremia.

1

The influx rate constant of the experimental membranes decrease with a resulting decrease of the calcium influx rate.
2

The experimental membranes transport a smaller amount of Ca2+ per mol of ATP split than the controls, i.e. their transport ratio is decreased.
3

The calcium permeability of the experimental membranes increases with a resulting decreased concentrating ability.
4

The phosphatide content but not the cholesterol content of the experimental membranes decreases with a consequent increase of the cholesterol/phosphatide ratio.
5

The fatty acid pattern of total phosphatides of the experimental membranes changes. A relative decrease of palmitic acid and oleic acid occurs and a relative increase of stearic, arachidonic and higher unsaturated fatty acids.
6

The altered lipid composition of the membranes does not change the temperature dependence of the kinetics.

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Language(s): eng - English
 Dates: 1975-06-091975-09-092008-06-281976-01
 Publication Status: Issued
 Pages: 7
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 Rev. Type: Peer
 Identifiers: DOI: 10.1111/j.1432-1033.1976.tb10013.x
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Title: European Journal of Biochemistry
Source Genre: Journal
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Publ. Info: Berlin : Published by Springer-Verlag on behalf of the Federation of European Biochemical Societies
Pages: - Volume / Issue: 61 (1) Sequence Number: - Start / End Page: 207 - 213 Identifier: ISSN: 0014-2956
CoNE: https://pure.mpg.de/cone/journals/resource/111097776606040