English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Evolution of macromolecular structure: a 'double tale' of biological accretion and diversification

Caetano-Anollés, D., Caetano-Anollés, K., & Caetano-Anollés, G. (2018). Evolution of macromolecular structure: a 'double tale' of biological accretion and diversification. Science Progress, 101(4), 360-383. doi:10.3184/003685018X15379391431599.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0002-C48C-3 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-C48D-2
Genre: Journal Article

Files

show Files
hide Files
:
1805.06487(3).pdf (Any fulltext), 2MB
 
File Permalink:
-
Name:
1805.06487(3).pdf
Description:
-
Visibility:
Restricted ( Max Planck Society (every institute); )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Creators

show
hide
 Creators:
Caetano-Anollés, Derek1, Author              
Caetano-Anollés, Kelsey1, Author
Caetano-Anollés, Gustavo1, Author
Affiliations:
1Department Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445635              

Content

show
hide
Free keywords: TRANSFER-RNA; ORIGIN; CLASSIFICATION; PROTEOMES; RIBOSOME; HISTORY; GROWTH; MODEL Education & Educational Research; Science & Technology - Other Topics;
 Abstract: The evolution of structure in biology is driven by accretion and diversification. Accretion brings together disparate parts to form bigger wholes. Divers cation provides opportunities for growth and innovation. Here, we review patterns and processes that are responsible for a 'double tale' of accretion and diversification at various levels of complexity, from proteins and nucleic acids to high-rise building structures in cities. Parts are at first weakly linked and associate variously. As they diversity, they compete with each other and are selected for performance. The emerging interactions constrain their structure and associations. This causes parts to self-organise into modules with tight linkage. In a second phase, variants of the modules evolve and become new parts for a new generative cycle of higher-level organisation. Evolutionary genomics and network biology support the 'double tale' of structural module creation and validate an evolutionary principle of maximum abundance that drives the gain and loss of modules.

Details

show
hide
Language(s): eng - English
 Dates: 2018-10-082018
 Publication Status: Published in print
 Pages: 24
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Science Progress
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Science Reviews Ltd.
Pages: - Volume / Issue: 101 (4) Sequence Number: - Start / End Page: 360 - 383 Identifier: ISSN: 0036-8504
CoNE: https://pure.mpg.de/cone/journals/resource/954927572872