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  MaxSynBio: Avenues towards creating cells from the bottom up

Schwille, P., Spatz, J. P., Landfester, K., Bodenschatz, E., Herminghaus, S., Sourjik, V., et al. (2018). MaxSynBio: Avenues towards creating cells from the bottom up. Angewandte Chemie International Edition in English, 57(41), 13382-13392. doi:10.1002/anie.201802288.

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 Creators:
Schwille, Petra, Author           
Spatz, Joachim P.1, Author           
Landfester, Katharina, Author
Bodenschatz, Eberhard, Author           
Herminghaus, Stephan, Author
Sourjik, Victor, Author
Erb, Tobias, Author
Bastiaens, Philippe, Author           
Lipowsky, Reinhard, Author           
Hyman, Anthony A., Author           
Dabrock, Peter, Author
Baret, Jean-Christophe, Author           
Vidaković-Koch, Tanja, Author           
Bieling, Peter, Author
Dimova, Rumiana, Author           
Mutschler, Hannes2, Author           
Robinson, Tom, Author           
Tang, T-Y Dora, Author           
Wegner, Seraphine, Author           
Sundmacher, Kai, Author           
Affiliations:
1Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_2364731              
2Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700              

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Free keywords: biotechnology, bottom-up design, microfluidics, protocells, synthetic biology
 Abstract: A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom‐up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non‐living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology.

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Language(s): eng - English
 Dates: 2018-04-032018-02-212018-05-112018-09-172018-10-04
 Publication Status: Published in print
 Pages: 11
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1002/anie.201802288
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Title: Angewandte Chemie International Edition in English
  Abbreviation : Angew. Chem. Int. Ed. Engl.
Source Genre: Journal
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Publ. Info: Weinheim : Wiley-VCH
Pages: - Volume / Issue: 57 (41) Sequence Number: - Start / End Page: 13382 - 13392 Identifier: ISSN: 0570-0833
CoNE: https://pure.mpg.de/cone/journals/resource/0570-0833