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  Noninvasive cerebral blood flow monitoring by a dye bolus method: Separation of extra- and intracerebral absorption changes by frequency-domain spectroscopy

Kohl-Bareis, M., Obrig, H., Steinbrink, J., Malak, J., Uludag, K., & Villringer, A. (2001). Noninvasive cerebral blood flow monitoring by a dye bolus method: Separation of extra- and intracerebral absorption changes by frequency-domain spectroscopy. In Proceedings of SPIE: Optical Tomography and Spectroscopy of Tissue IV (pp. 296-300). SPIE Digital Library. doi:10.1117/12.434501.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0003-4368-D Version Permalink: https://hdl.handle.net/21.11116/0000-0003-5033-9
Genre: Conference Paper

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Kohl-Bareis, Matthias1, Author
Obrig, Hellmuth1, Author           
Steinbrink, Jens1, Author
Malak, Jasmin1, Author
Uludag, Kamil1, Author
Villringer, Arno1, Author           
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1External Organizations, ou_persistent22              

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 Abstract: Tracking a bolus of contrast agent traveling through the cerebral vasculature provides a measure of the blood supply and the blood flow velocity in the respective cerebral tissue. This principle has been the basis for the first approaches in functional MR imaging and is of great value when investigating stroke and other vascularly compromised patients. While the bolus measurement is a standard procedure in clinical MR imaging, optical bolus tracking has not yet become a reliable protocol. Here optical absorption changes induced by bolus signals of the dye indocyanine- green are studied by near infrared spectroscopy on volunteers. The aim is to assess the latency and shape of the absorption change.

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Language(s): eng - English
 Dates: 2001-06-292001
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1117/12.434501
 Degree: -

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Title: BIOS 2001 The International Symposium on Biomedical Optics
Place of Event: San Jose, CA
Start-/End Date: 2001-01-20 - 2001-01-26

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Title: Proceedings of SPIE: Optical Tomography and Spectroscopy of Tissue IV
Source Genre: Proceedings
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Publ. Info: SPIE Digital Library
Pages: 614 S. Volume / Issue: 4250 Sequence Number: - Start / End Page: 296 - 300 Identifier: ISBN: 978-0819439284