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  Reorganization of the cerebro-cerebellar network of language production in patients with congenital left-hemispheric brain lesions

Lidzba, K., Wilke, M., Staudt, M., Krägeloh-Mann, I., & Grodd, W. (2008). Reorganization of the cerebro-cerebellar network of language production in patients with congenital left-hemispheric brain lesions. Brain and Language, 106(3), 204-210. doi:10.1016/j.bandl.2007.11.003.

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Lidzba, K, Author
Wilke, M, Author
Staudt, M, Author
Krägeloh-Mann, I, Author
Grodd, W1, Author           
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1External Organizations, ou_persistent22              

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 Abstract: Patients with congenital lesions of the left cerebral hemisphere may reorganize language functions into the right hemisphere. In these patients, language production is represented homotopically to the left-hemispheric language areas. We studied cerebellar activation in five patients with congenital lesions of the left cerebral hemisphere to assess if the language network is reorganized completely in these patients, i.e. including also cerebellar language functions. As compared to a group of controls matched for age, sex, and verbal IQ, the patients recruited an area not in the right but in the left cerebellar hemisphere. The extent of laterality of the cerebellar activation correlated significantly with the laterality of the frontal activation. We suggest that the developing brain reacts to early focal lesions in the left hemisphere with a mirror-image organization of the entire cerebro-cerebellar network engaged in speech production.

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 Dates: 2008-09
 Publication Status: Issued
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 Identifiers: DOI: 10.1016/j.bandl.2007.11.003
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Title: Brain and Language
Source Genre: Journal
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Publ. Info: Orlando, Fla. : Academic Press
Pages: - Volume / Issue: 106 (3) Sequence Number: - Start / End Page: 204 - 210 Identifier: ISSN: 0093-934X
CoNE: https://pure.mpg.de/cone/journals/resource/954922647078