English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Quantitative magnetic resonance imaging of perfusion using magnetic labeling of water proton spins within the detection slice

Schwarzbauer, C., Morrissey, S. P., & Haase, A. (1996). Quantitative magnetic resonance imaging of perfusion using magnetic labeling of water proton spins within the detection slice. Magnetic Resonance in Medicine, 35(3), 540-546. doi:10.1002/mrm.1910350413.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0003-3A81-A Version Permalink: http://hdl.handle.net/21.11116/0000-0003-3A82-9
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Schwarzbauer, Christian1, 2, Author              
Morrissey, Sean Patrick2, Author
Haase, Axel2, Author
Affiliations:
1MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634574              
2External Organizations, ou_persistent22              

Content

show
hide
Free keywords: magnetic resonance imaging; spin labeling; regional cerebral blood flow; perfusion
 Abstract: A technique for noninvasive quantitative magnetic resonance imaging of perfusion is presented. It relies on using endogenous water as a freely diffusible tracer. Tissue water proton spins are magnetically labeled by slice-selective inversion, and longitudinal relaxation within the slice is detected using a fast gradient echo magnetic resonance imaging technique. Due to blood flow, nonexcited spins are washed into the slice resulting in an acceleration of the longitudinal relaxation process. Incorporating this phenomenon into the Bloch equation yields an expression that allows quantification of perfusion on the basis of a slice-selective and a nonselective inversion recovery experiment. Based on this technique, quantitative parameter maps of the regional cerebral blood flow (rCBF) were obtained from eight rats. Evaluation of regions of interest within the cerebral hemispheres yielded an average rCBF value of 104 +/- 21 ml/min/100 g, which increased to 219 +/- 30 ml/min/100 g during hypercapnia. The measured rCBF values are in good agreement with previously reported literature values.

Details

show
hide
Language(s): eng - English
 Dates: 1995-11-021995-03-011995-11-042011-02-031996-04
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1002/mrm.1910350413
PMID: 8992204
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Magnetic Resonance in Medicine
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 35 (3) Sequence Number: - Start / End Page: 540 - 546 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149