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Abstract:
Spectral highly resolved Z-spectra in vivo are desirable for e.g. peak assignment in quantitative CEST, identification of CEST signal substructures, machine learning approaches or sequence parameter
optimization. We showed that the acquisition of densely sampled Z-spectra is possible. By applying latest developments in 3D image acquisition and post-processing including motion correction, steady state compensation and spectral denoising, we overcame limitations in measurement time.