Fat corrected APT-CEST in the human breast

Zimmermann, F; Korzowski, A; Schuenke, P; Breitling, J; Zaiss, M; Paech, D; Ladd, ME; Bachert, P; Goerke, S

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Fat corrected APT-CEST in the human breast

Zimmermann, F., Korzowski, A., Schuenke, P., Breitling, J., Zaiss, M., Paech, D., et al. (2018). Fat corrected APT-CEST in the human breast. In 7th International Workshop on Chemical Exchange Saturation Transfer (CEST 2018) (pp. 73).

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Item Permalink: https://hdl.handle.net/21.11116/0000-0003-450A-5 Version Permalink: https://hdl.handle.net/21.11116/0000-0003-450B-4

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http://www.medmeeting.org/Upload/user/1268647/file/20181123/20181123135354_7309.pdf (Abstract) Open Access status unknown

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Creators:
Zimmermann, F, Author
Korzowski, A, Author
Schuenke, P, Author
Breitling, J, Author
Zaiss, M^{1, 2}, Author
Paech, D, Author
Ladd, ME, Author
Bachert, P, Author
Goerke, S, Author

Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794

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Abstract: CEST in the mammary gland is affected by lipid signals1-5 not only causing strong pseudo rNOE artifacts4, but also leading to an incorrect normalization of the Z-spectrum in the spectral region of the amide proton transfer (APT) signal. Here, we propose to approximate the total fat signal by the residual magnetization at Δω = 0 ppm. This enables the correction of Z-spectra for fat signal induced artifacts without any
additional measurements and thus fat independent quantitative APT-CEST imaging.

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Dates: Date issued: 2018-11

Publication Status: Issued

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Title: 7th International Workshop on Chemical Exchange Saturation Transfer (CEST 2018)

Place of Event: Beijing, China

Start-/End Date: 2018-11-12 - 2018-11-15

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Title: 7th International Workshop on Chemical Exchange Saturation Transfer (CEST 2018)

Source Genre: Proceedings

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Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 73 Identifier: -