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Free keywords:
Serine Protease; Glutathione Reductase; Amino Acid Change; Distance Distribution; Soap Film
Abstract:
Proteins undergo changes in the course of species evolution. As a consequence evolutionary distances between species can be derived from differences between their proteins, i.e. protein structures can be used for the taxonomy of species (Wu et al., 1974). Based on the wealth of structural data on proteins, we know that during evolution the first structural changes occur in functionally unimportant regions of the protein. These are for example amino acid changes in the surface areas far apart from the active center of a protein.
