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Free keywords:
Early-onset osteoporosis; Genetics; Monogenic bone disorders; Pregnancy-associated osteoporosis; Treatment
Abstract:
Pregnancy was found to be a skeletal risk factor promoting the initial onset of previously unrecognized monogenic bone disorders, thus explaining a proportion of cases with pregnancy-associated osteoporosis. Therapeutic measures should focus in particular on the normalization of the disturbed calcium homeostasis in order to enable the partial skeletal recovery.