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  From Epigenetic Associations to Biological and Psychosocial Explanations in Mental Health

Renzi, C., Provencal, N., Bassil, K. C., Evers, K., Kihlbom, U., Radford, E. J., et al. (2018). From Epigenetic Associations to Biological and Psychosocial Explanations in Mental Health. In B. P. F. Rutten (Ed.), NEUROEPIGENETICS AND MENTAL ILLNESS (pp. 299-323). Cambridge: ELSEVIER ACADEMIC PRESS.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0003-6751-E Version Permalink: https://hdl.handle.net/21.11116/0000-0003-FCB9-1
Genre: Book Chapter

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 Creators:
Renzi, Chiara1, Author
Provencal, Nadine1, Author
Bassil, Katherine C.1, Author
Evers, Kathinka1, Author
Kihlbom, Ulrik1, Author
Radford, Elizabeth J.1, Author
Koupil, Ilona1, Author
Mueller-Myhsok, Bertram1, 2, Author           
Hansson, Mats G.1, Author
Rutten, Bart P. F.1, Author
Affiliations:
1External Organizations, ou_persistent22              
2Dept. Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Max Planck Society, ou_2035295              

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Free keywords: GENE-ENVIRONMENT INTERACTIONS; GENOME-WIDE ASSOCIATION; BIOPSYCHOSOCIAL MODEL; SOCIOECONOMIC-STATUS; SELECTIVE ATTENTION; RESEARCH STRATEGIES; BRAIN-DEVELOPMENT; NETWORK MEDICINE; DNA METHYLATION; MATERNAL-CAREBiochemistry & Molecular Biology; Neurosciences & Neurology;
 Abstract: The development of mental disorders constitutes a complex phenomenon driven by unique social, psychological and biological factors such as genetics and epigenetics, throughout an individual's life course. Both environmental and genetic factors have an impact on mental health phenotypes and act simultaneously to induce changes in brain and behavior. Here, we describe and critically evaluate the current literature on gene-environment interactions and epigenetics on mental health by highlighting recent human and animal studies. We furthermore review some of the main ethical and social implications concerning gene-environment interactions and epigenetics and provide explanations and suggestions on how to move from statistical and epigenetic associations to biological and psychological explanations within a multi-disciplinary and integrative approach of understanding mental health.

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Language(s): eng - English
 Dates: 2018
 Publication Status: Issued
 Pages: 25
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 000452377300013
DOI: 10.1016/bs.pmbts.2018.04.011
 Degree: -

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Title: NEUROEPIGENETICS AND MENTAL ILLNESS
  Alternative Title : Prog. Molec. Biol. Transl. Sci.
  Alternative Title : PROG MOL BIOL TRANSL
Source Genre: Book
 Creator(s):
Rutten, Bart P. F., Editor
Affiliations:
-
Publ. Info: Cambridge : ELSEVIER ACADEMIC PRESS
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 299 - 323 Identifier: ISSN: 1877-1173
ISBN: 978-0-12-812592-2

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Title: Progress in Molecular Biology and Translational Science
  Alternative Title : PROG MOL BIOL TRANSL
  Alternative Title : Prog. Molec. Biol. Transl. Sci.
Source Genre: Series
 Creator(s):
-, Editor              
Affiliations:
-
Publ. Info: Cambridge : ELSEVIER ACADEMIC PRESS
Pages: - Volume / Issue: 158 Sequence Number: - Start / End Page: 299 - 314 Identifier: ISSN: 1877-1173