English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Working memory training integrates visual cortex into beta-band networks in congenitally bind individuals

Rimmele, J. M., Gudi-Mindermann, H., Nolte, G., Roeder, B., & Engel, K. A. (2019). Working memory training integrates visual cortex into beta-band networks in congenitally bind individuals. NeuroImage, 194, 259-271. doi:10.1016/j.neuroimage.2019.03.003.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0003-6C57-3 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-D3BD-A
Genre: Journal Article

Files

show Files
hide Files
:
1-s2.0-S1053811919301703-main.pdf (Publisher version), 3MB
Name:
1-s2.0-S1053811919301703-main.pdf
Description:
OA
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
2019
Copyright Info:
-

Locators

show

Creators

show
hide
 Creators:
Rimmele, Johanna Maria1, Author              
Gudi-Mindermann, H., Author
Nolte, G., Author
Roeder, B., Author
Engel, K. A., Author
Affiliations:
1Department of Neuroscience, Max Planck Institute for Empirical Aesthetics, Max Planck Society, ou_2421697              

Content

show
hide
Free keywords: Congenitally blind Functional connectivity Oscillations Training Working memory
 Abstract: Congenitally blind individuals have been shown to activate the visual cortex during non-visual tasks. The neuronal mechanisms of such cross-modal activation are not fully understood. Here, we used an auditory working memory training paradigm in congenitally blind and in sighted adults. We hypothesized that the visual cortex gets integrated into auditory working memory networks, after these networks have been challenged by training. The spectral profile of functional networks was investigated which mediate cross-modal reorganization following visual deprivation. A training induced integration of visual cortex into task-related networks in congenitally blind individuals was expected to result in changes in long-range functional connectivity in the theta-, beta- and gamma band (imaginary coherency) between visual cortex and working memory networks. Magnetoencephalographic data were recorded in congenitally blind and sighted individuals during resting state as well as during a voicebased working memory task; the task was performed before and after working memory training with either auditory or tactile stimuli, or a control condition. Auditory working memory training strengthened theta-band (2.5–5 Hz) connectivity in the sighted and beta-band (17.5–22.5 Hz) connectivity in the blind. In sighted participants, theta-band connectivity increased between brain areas typically involved in auditory working memory (inferior frontal, superior temporal, insular cortex). In blind participants, beta-band networks largely emerged during the training, and connectivity increased between brain areas involved in auditory working memory and as predicted, the visual cortex. Our findings highlight long-range connectivity as a key mechanism of functional reorganization following congenital blindness, and provide new insights into the spectral characteristics of functional network connectivity.

Details

show
hide
Language(s): eng - English
 Dates: 2019-02-252018-06-272019-03-032019-03-072019-07-01
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.neuroimage.2019.03.003
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: NeuroImage
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Orlando, FL : Academic Press
Pages: - Volume / Issue: 194 Sequence Number: - Start / End Page: 259 - 271 Identifier: ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166