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  Towards robust – and accurate – QSM in cortical and sub-cortical regions of the human brain at 9.4T: the influence of masking

Hagberg, G., Tuzzi, E., Loureiro, J., Ethofer, T., Pohmann, R., Bause, J., et al. (2019). Towards robust – and accurate – QSM in cortical and sub-cortical regions of the human brain at 9.4T: the influence of masking. In ISMRM 27th Annual Meeting & Exhibition.

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Item Permalink: http://hdl.handle.net/21.11116/0000-0003-9D08-4 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-C720-8
Genre: Meeting Abstract

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 Creators:
Hagberg, G1, 2, Author              
Tuzzi, E, Author              
Loureiro, J, Author              
Ethofer, T, Author
Pohmann, R1, 2, Author              
Bause, J1, 2, Author              
Martin, P, Author
Pavlova, M, Author
Himmelbach, M, Author              
Zeller , A, Author
Laske, E, Author
Fallgatter, A, Author
Scheffler, K1, 2, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Quantitative susceptibility mapping (QSM) targets a fundamental MR-parameter but is problematic due to the presence of a strong background and local field variations. These may cause multiple phase wraps which are particularly prominent at high fields and long echo-times. We propose automated tissue masking excluding brain areas with excessive phase wraps and show how this approach can improve the quality of QSM. Performance was evaluated with regard to iron quantification in subcortical and cortical areas, and was compared with R2* maps in the same 21 subjects aged 19-56y and literature values.

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 Dates: 2019-05
 Publication Status: Published online
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Title: 27th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2019)
Place of Event: Montréal, QC, Canada
Start-/End Date: 2019-05-11 - 2019-05-16

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Title: ISMRM 27th Annual Meeting & Exhibition
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0313 Start / End Page: - Identifier: -