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  Multi-echo segmented diffusion-weighted MRI for ex-vivo whole-brain measurements with 300mT/m gradients

Eichner, C., Mildner, T., Paquette, M., Schlumm, T., Crockford, C., Wittig, R. M., et al. (2019). Multi-echo segmented diffusion-weighted MRI for ex-vivo whole-brain measurements with 300mT/m gradients. In Proceedings of the 27th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM).

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Item Permalink: http://hdl.handle.net/21.11116/0000-0003-ABEE-1 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-B0A0-0
Genre: Meeting Abstract

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 Creators:
Eichner, Cornelius1, Author              
Mildner, Toralf2, Author              
Paquette, Michael1, Author              
Schlumm, Torsten2, Author              
Crockford, Catherine3, Author              
Wittig, Roman M.3, Author              
Kirilina, Evgeniya4, Author              
Jäger, Carsten4, Author              
Möller, Harald E.2, Author              
Weiskopf, Nikolaus4, Author              
Friederici, Angela D.1, Author              
Anwander, Alfred1, Author              
Affiliations:
1Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634551              
2Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634558              
3Department of Primatology, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_1497674              
4Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205649              

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 Abstract: We provide a novel method to increase SNR of segmented diffusion-weighted EPI acquisitions. Multiple gradient echoes were acquired after each diffusion-preparation and combined in an SNR-optimized way using weightings from quantitative T2* maps. The combination of diffusion-weighted echoes yielded an SNR-gain of 58% compared to single-echo dMRI data with an increase in the segmented readout duration by only 23.1 ms. The multi-echo diffusion MRI acquisition and combination were employed to acquire high-quality ex-vivo diffusion-weighted MRI data from a wild chimpanzee brain.

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 Dates: 2019-05-11
 Publication Status: Published online
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Project name : Computational Connectomics / SPP 2041
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Funding organization : German Research Foundation (DFG)

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Title: Proceedings of the 27th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)
Source Genre: Proceedings
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Pages: - Volume / Issue: 27 Sequence Number: 3510 Start / End Page: - Identifier: -