English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Genetic diversity of HLA system in two populations from Durango, Mexico: Durango city and rural Durango

González-Medina, L., Barquera, R., Delgado-Aguirre, H., Clayton, S., Adalid-Sáinz, C., Arrieta-Bolaños, E., et al. (2019). Genetic diversity of HLA system in two populations from Durango, Mexico: Durango city and rural Durango. Human Immunology. doi:10.1016/j.humimm.2019.06.005.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0003-C3E4-F Version Permalink: http://hdl.handle.net/21.11116/0000-0003-C3E5-E
Genre: Journal Article

Files

show Files
hide Files
:
shh2250.pdf (Preprint), 3MB
 
File Permalink:
-
Name:
shh2250.pdf
Description:
In Press, Corrected Proof
Visibility:
Private
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
González-Medina, Liliana, Author
Barquera, Rodrigo1, Author              
Delgado-Aguirre, Héctor, Author
Clayton, Stephen1, Author              
Adalid-Sáinz, Carmen, Author
Arrieta-Bolaños, Esteban, Author
Pacheco-Ubaldo, Hanna, Author
Hernández-Zaragoza, Diana Iraíz, Author
Escareño-Montiel, Néstor, Author
Morán-Martínez, Javier, Author
Bravo-Acevedo, Alicia, Author
Lona-Sánchez, Abraham, Author
González-Martínez, Marisela del Rocío, Author
Jaramillo-Rodríguez, Yolanda, Author
Salgado-Adame, Antonio, Author
la Cruz, Federico Juárez-de, Author
Zúñiga, Joaquín, Author
Yunis, Edmond J., Author
Bekker-Méndez, Carolina, Author
Granados, Julio, Author
Affiliations:
1Archaeogenetics, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074310              

Content

show
hide
Free keywords: HLA, Immunogenetics, Population genetics, Durango, Admixture
 Abstract: We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 479 Mexicans from the state of Durango living in Durango city (N = 153) and rural communities (N = 326), to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes found in the state of Durango include eight Native American and two European haplotypes. Admixture estimates revealed that the main genetic components in Durango are European (54.34 ± 1.68) and Native American (45.66 ± 2.24), while African genetic component was virtually absent (0.00 ± 2.03). However, African haplotypes could be estimated at a proportion of 9.13.

Details

show
hide
Language(s): eng - English
 Dates: 2019-06-11
 Publication Status: Published online
 Pages: 3
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.humimm.2019.06.005
Other: shh2250
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Human Immunology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York, N.Y. : Elsevier
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: - Identifier: ISSN: 0198-8859
CoNE: https://pure.mpg.de/cone/journals/resource/954925492912