English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The interaction of acute and chronic stress impairs model-based behavioral control

Radenbach, C., Reiter, A., Engert, V., Sjoerds, Z., Villringer, A., Heinze, H.-J., et al. (2015). The interaction of acute and chronic stress impairs model-based behavioral control. Psychoneuroendocrinology, 53, 268-280. doi:10.1016/j.psyneuen.2014.12.017.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0003-FEED-5 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-FEEF-3
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Radenbach, Christoph1, Author              
Reiter, Andrea1, 2, Author              
Engert, Veronika3, Author              
Sjoerds, Zsuzsika1, Author              
Villringer, Arno4, 5, 6, 7, Author              
Heinze, Hans-Jochen8, 9, Author
Deserno, Lorenz1, 9, 10, Author              
Schlagenhauf, Florian1, 10, Author              
Affiliations:
1Max Planck Fellow Group Cognitive and Affective Control of Behavioural Adaptation, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_1753350              
2International Max Planck Research School on Neuroscience of Communication, Leipzig, Germany, ou_persistent22              
3Department Social Neuroscience, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634552              
4Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
5Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              
6Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Germany, ou_persistent22              
7Berlin School of Mind and Brain, Humboldt University Berlin, Germany, ou_persistent22              
8Department of Behavioral Neurology, Leibniz Institute for Neurobiology, Magdeburg, Germany, ou_persistent22              
9Department of Neurology, Otto von Guericke University Magdeburg, Germany, ou_persistent22              
10Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Germany, ou_persistent22              

Content

show
hide
Free keywords: Acute/chronic stress; Cortisol; Computational modeling; Reinforcement learning; Model-based/model-free decision-making; Behavioral control
 Abstract: It is suggested that acute stress shifts behavioral control from goal-directed, model-based toward habitual, model-free strategies. Recent findings indicate that interindividual differences in the cortisol stress response influence model-based decision-making. Although not yet investigated in humans, animal studies show that chronic stress also shifts decision-making toward more habitual behavior. Here, we ask whether acute stress and individual vulnerability factors, such as stress reactivity and previous exposure to stressful life events, impact the balance between model-free and model-based control systems. To test this, 39 male participants (21–30 years old) were exposed to a potent psychosocial stressor (Trier Social Stress Test) and a control condition in a within-subjects design before they performed a sequential decision-making task which evaluates the balance between the two systems. Physiological and subjective stress reactivity was assessed before, during, and after acute stress exposure. By means of computational modeling, we demonstrate that interindividual variability in stress reactivity predicts impairments in model-based decision-making. Whereas acute psychosocial stress did not alter model-based behavioral control, we found chronic and acute stress to interact in their detrimental effect on decision-making: subjects with high but not low chronic stress levels as indicated by stressful life events exhibited reduced model-based control in response to acute psychosocial stress. These findings emphasize that stress reactivity and chronic stress play an important role in mediating the relationship between stress and decision-making. Our results might stimulate new insights into the interplay between chronic and acute stress, attenuated model-based control, and the pathogenesis of various psychiatric diseases.

Details

show
hide
Language(s): eng - English
 Dates: 2014-09-122014-12-022015-01-062015-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.psyneuen.2014.12.017
PMID: 25662093
Other: Epub 2015
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Psychoneuroendocrinology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Oxford : Pergamon
Pages: - Volume / Issue: 53 Sequence Number: - Start / End Page: 268 - 280 Identifier: ISSN: 0306-4530
CoNE: /journals/resource/954925514499