English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  Relationships between structure, in vivo function and long-range axonal target of cortical pyramidal tract neurons

Rojas-Piloni, G., Guest, J. M., Egger, R., Johnson, A. S., Sakmann, B., & Oberlaender, M. (2017). Relationships between structure, in vivo function and long-range axonal target of cortical pyramidal tract neurons. Nature Communications, 870. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/29021587.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/21.11116/0000-0003-D536-0 Version Permalink: https://hdl.handle.net/21.11116/0000-0005-B903-7
Genre: Journal Article
Alternative Title : Nature Communications

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Rojas-Piloni, Gerardo1, Author
Guest, Jason M.1, Author
Egger, Robert1, Author
Johnson, Andrew S.1, Author
Sakmann, Bert1, Author
Oberlaender, Marcel1, Author
Affiliations:
1Max Planck Florida Institute for Neuroscience, Max Planck Society, One Max Planck Way, Jupiter FL 33458, USA, ou_1950288              

Content

show
hide
Free keywords: -
 Abstract: Pyramidal tract neurons (PTs) represent the major output cell type of the neocortex. To investigate principles of how the results of cortical processing are broadcasted to different downstream targets thus requires experimental approaches, which provide access to the in vivo electrophysiology of PTs, whose subcortical target regions are identified. On the example of rat barrel cortex (vS1), we illustrate that retrograde tracer injections into multiple subcortical structures allow identifying the long-range axonal targets of individual in vivo recorded PTs. Here we report that soma depth and dendritic path lengths within each cortical layer of vS1, as well as spiking patterns during both periods of ongoing activity and during sensory stimulation, reflect the respective subcortical target regions of PTs. We show that these cellular properties result in a structure-function parameter space that allows predicting a PT's subcortical target region, without the need to inject multiple retrograde tracers.The major output cell type of the neocortex

Details

show
hide
Language(s):
 Dates: 2017
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: URI: http://www.ncbi.nlm.nih.gov/pubmed/29021587
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Nature Communications
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 870 Identifier: -