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  Simple mechanics of protein machines

Flechsig, H., & Mikhailov, A. S. (2019). Simple mechanics of protein machines. Interface, 16(155): 20190244. doi:10.1098/rsif.2019.0244.

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 Creators:
Flechsig, Holger1, Author
Mikhailov, Alexander S.1, 2, Author           
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1Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kakuma-machi, 920-1192 Kanazawa, Japan, ou_persistent22              
2Physical Chemistry, Fritz Haber Institute, Max Planck Society, ou_634546              

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 Abstract: While belonging to the nanoscale, protein machines are so complex that tracing even a small fraction of their cycle requires weeks of calculations on supercomputers. Surprisingly, many aspects of their operation can be however already reproduced by using very simple mechanical models of elastic networks. The analysis suggests that, similar to other self-organized complex systems, functional collective dynamics in such proteins is effectively reduced to a low-dimensional attractive manifold.

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Language(s): eng - English
 Dates: 2019-04-012019-05-282019-06-192019-06-05
 Publication Status: Issued
 Pages: 13
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1098/rsif.2019.0244
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Title: Interface
  Other : J. R. Soc. Interface
Source Genre: Journal
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Publ. Info: London : Royal Society
Pages: 13 Volume / Issue: 16 (155) Sequence Number: 20190244 Start / End Page: - Identifier: ISSN: 1742-5689
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000018840_1