English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Cerebral blood flow measurements using arterial spin labeling

Çavuşoğlu, M., & Uludag, K. (2007). Cerebral blood flow measurements using arterial spin labeling. In 8th Conference of Tuebingen Junior Neuroscientists (NeNa 2007) (pp. 16).

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/21.11116/0000-0003-EF79-9 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-EF7A-8
Genre: Meeting Abstract

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Çavuşoğlu, M1, 2, Author              
Uludag, K1, 2, Author              
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: Arterial Spin Labeling (ASL) is a magnetic resonance imaging (MRI) method to map the cerebral blood flow (CBF). ASL present a non-invasive alternative to the contrast agent techniques used typically to study vascular and neuronal diseases such as stroke, arteriostenosis, schizophrenia, alzheimer, epilepsy …. ASL techniques are capable of providing quantitative information about local tissue blood flow by tracking the inflow of magnetically labeled arterial blood into an imaging slice. The delivery of the tagged water to each image voxel is measured. Because ASL is completely noninvasive, the tagging can be repeated many times to obtain a high signal-to-noise ratio (SNR). ASL produces perfusion maps of human brain with higher spatial and temporal resolution than any other existing technique. Furthermore, ASL has extensively been used to study brain function mostly simultaneously with the blood oxygenated level dependent (BOLD) signal. BOLD signal provide a high functional contrast to noise ratio, but the analysis and interpretation of BOLD contrast functional data is complicated by the fact that the MRI signal change is related to the underlying neuronal activation through CBF, CBV and oxidative metabolism (CMRO2). In contrast to baseline BOLD signal, baseline CBF measured using ASL provides valuable information of the brain’s respective state. In addition, ASL techniques are an important tool to study the physiological basis of functional neuroimaging techniques such as BOLD signal. In the study presented at the conference, we evaluated critically three different ASL sequences and compared established methods to determine absolute values of CBF from ASL data.

Details

show
hide
Language(s):
 Dates: 2007-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: -
 Degree: -

Event

show
hide
Title: 8th Conference of Tuebingen Junior Neuroscientists (NeNa 2007)
Place of Event: Freudenstadt, Germany
Start-/End Date: 2007-11-26 - 2007-11-28

Legal Case

show

Project information

show

Source 1

show
hide
Title: 8th Conference of Tuebingen Junior Neuroscientists (NeNa 2007)
Source Genre: Proceedings
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: T11 Start / End Page: 16 Identifier: -