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  MaxSynBio: Avenues Towards Creating Cells from the Bottom Up

Schwille, P., Spatz, J., Landfester, K., Bodenschatz, E., Herminghaus, S., Sourjik, V., et al. (2018). MaxSynBio: Avenues Towards Creating Cells from the Bottom Up. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57(41), 13382-13392. doi:10.1002/anie.201802288.

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Schwille, P., Author
Spatz, J., Author
Landfester, K., Author
Bodenschatz, E., Author
Herminghaus, S., Author
Sourjik, V.1, Author           
Erb, T. J.2, Author           
Bastiaens, P., Author
Lipowsky, R., Author
Hyman, A., Author
Dabrock, P., Author
Baret, J., Author
Vidakovic-Koch, T., Author
Bieling, P., Author
Dimova, R., Author
Mutschler, H., Author
Robinson, T., Author
Tang, T., Author
Wegner, S., Author
Sundmacher, K., Author
Affiliations:
1Microbial Networks, Department of Systems and Synthetic Microbiology, Max Planck Institute for Terrestrial Microbiology, Max Planck Society, Karl-von-Frisch-Strasse 10, D-35043 Marburg, DE, ou_3266309              
2Understanding and Building Metabolism, Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Max Planck Society, Karl-von-Frisch-Strasse 10, D-35043 Marburg, DE, ou_3266303              

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 Abstract: A large German research consortium mainly within the Max Planck Society ("MaxSynBio") was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom-up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non-living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology.

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 Dates: 2018-10-08
 Publication Status: Issued
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 Rev. Type: -
 Identifiers: eDoc: 747938
ISI: 000446306600002
DOI: 10.1002/anie.201802288
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Title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Source Genre: Journal
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Pages: - Volume / Issue: 57 (41) Sequence Number: - Start / End Page: 13382 - 13392 Identifier: ISSN: 1433-7851